Weakness of Registration Bioequivalent Drugs

The case for standardizing the appearance of bioequivalent medications.

Essential drugs and registration of pharmaceuticals: the Sri Lankan experience.

Many factors influence the regulation of pharmaceuticals in a country. The essential drugs concept, formulated by the World Health Organization to assist developing countries in selecting appropriate drugs, also provides a basis for regulation. Sri Lanka has long regulated pharmaceuticals as part of its health policy. Over 70% of 3436 pharmaceutical product registrations were found to be drugs ...

Consistency in the safety labeling of bioequivalent medications.

PURPOSE Bioequivalent medications are required by the Food and Drug Administration to have identical warnings on their labels. This requirement has both clinical and legal importance, yet has never been validated. We sought to determine the real-world consistency of electronic labeling for bioequivalent drugs from different manufacturers. METHODS Using natural language processing, we indexed ...

Zanaflex Capsulestm Are Not Bioequivalent to Zanaflex® Tablets In

Pyramidal weakness.

The signs associated with an upper motor neurone syndrome vary considerably between text books. Often included are loss of dexterous, rapid and fractionated voluntary movements, variation of movement with mode of activation (prime mover, synergist, antagonist), weakness, various postural signs (eg, pronator drift), time-dependent tonal and tendon reflex changes and the extensor plantar response...